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This project is collaborated between The Forsyth Institute (TFI) and The Institute for Genomic Research (TIGR), and is funded by National Institute of Dental and Craniofacial Research (NIDCR)


To analyze and annotate the sequence of P. gingivalis strain W83

A variety of computer programs will be used to find open reading frames (ORFs) and to relate as many ORFs as possible to proteins of known and unknown function by similarity searches against databases. The sequence will be analyzed to identify a number of features, including metabolic pathways, virulence factors, and exported proteins. DNA structural motifs (such as promoters, replication origins and repeat elements) will be identified by the use of dedicated algorithms as illustrated previously. All genes for rRNA, and small RNAs, such as tRNA, 4.5S, 6S, 10S, and RNAse P, will be identified by searching the P. gingivalis DNA sequence against the GenBank DNA database.

This page is created and maintained by Drs. Margaret Duncan, Floyd Dewhirst, and Tsute Chen, Department of Molecular Genetics, The Forsyth Institute .

Last modified on 02/20/2002

Copyright 2000, 2001, 2002 by The Forsyth Institute