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This project is collaborated between The Forsyth Institute (TFI) and The Institute for Genomic Research (TIGR), and is funded by National Institute of Dental and Craniofacial Research (NIDCR)

Periondontal Pathogens

The change from periodontal health to disease is associated with the displacement of a predominantly gram-positive bacterial flora in the gingival crevice by gram-negative anaerobes. A small number of gram-negative species have been consistently associated with specific forms of periodontal disease, i.e., Porphyromonas gingivalis with chronic and severe adult periodontitis; Actinobacillus actinomycetemcomitans with localized juvenile periodontitis; and Prevotella intermedia and Treponema denticola with acute necrotizing gingivitis (reviewed by Holt and Bramanti, 1991; Haffajee and Socransky, 1994).


This page is created and maintained by Drs. Margaret Duncan, Floyd Dewhirst, and Tsute Chen, Department of Molecular Genetics, The Forsyth Institute .

Last modified on 02/20/2002

Copyright 2000, 2001, 2002 by The Forsyth Institute